DDEL-09David I. Sandberg1, Natasha Kharas1, , Bangning Yu1, Christopher F. Janssen1, Amanda Trimble1, Leomar Y. Ballester1, Rajan Patel1, Afroz S. Mohammad1, William F. Elmquist2, Rachael W. Sirianni121 McGovern Medical School, University of Texas Health Science...
Publications
PNOC015: An Open Label Single Arm Study of MTX110 Delivered by Convection-enhanced Delivery (CED) in Patients with Diffuse Intrinsic Pontine Glioma (DIPG) Previously Treated with External Beam Radiation Therapy
Sabine Mueller, Cassie Kline, Javier Villanueva-Meyer, Carly Hoffman, Shannon Raber, Erin Bonner, Javad Nazarian, Shannon Lundy, Annette Molinaro, Michael Prados, Mariella Filbin, Nalin Gupta Disclosures Research support from:NovartisBristol Meyers...
A Phase I study examining the feasibility of intermittent convection-enhanced delivery (CED) of MTX110 for the treatment of children with newly diagnosed diffuse midline gliomas
https://clinicaltrials.gov/ct2/show/NCT04264143 Stergios Zacharoulis , MD, Columbia University Medical Center, New York, USA Convection Enhanced Delivery (CED) Basic Principles The infusion of drugs under controlled pressure to the brain parenchyma via targeted...
Efficacy of soluble panobinostat (MTX110) in preclinical models of adult glioblastoma
David M. Ashley1, Stephen T. Keir1, Martin A. Roskoski1, Seethalakshmi Hariharan1, Rhian Davies2, Ben Williams2, Stephen JP Damment2 & Kelly Conlon2 - 1. Preston Robert Tisch Brain Tumor Centre, Duke University, Durham NC 27710, 2. Midatech Pharma Ltd, Cardiff, UK...
Singleton et al: The distribution, clearance, and brainstem toxicity of panobinostat administered by convection-enhanced delivery
William G. B. Singleton, PhD, MRCS,1 Alison S. Bieneman, PhD,1 Max Woolley, PhD,1,2 David Johnson, PhD,1,2 Owen Lewis, BEng,2 Marcella J. Wyatt, MSc,1 Stephen J. P. Damment, PhD,3 Lisa J. Boulter, BSc,1 Clare L. Killick-Cole, PhD,1 Daniel J. Asby, PhD,1 and Steven S....